Discover Brigham Drug Allergy Research

Discover Brigham Drug Allergy Research

On October 7, 2015, Discover Brigham highlighted the cutting-edge biomedical investigations of more than 3,000 researchers at Brigham and Women’s Hospital (BWH). 

Maria Castells, MD, PhD, Director of Drug Hypersensitivity and Desensitization Center, Tanya Laidlaw, MD, Director of Translational Research in Allergy and Paige Wickner, MD, MPH, Director of Quality and Safety for Allergy and Immunology from the BWH Division of Rheumatology, Immunology and Allergy, discussed their research on drug allergies at Discover Brigham.

According to the American Academy of Allergy, Asthma & Immunology, the most frequent types of drug allergies are skin rashes (particularly hives), itching, respiratory problems, and swelling, such as in the face. Anaphylaxis, a particularly severe allergic response, can be fatal if untreated.

Dr. Castells’ research focuses on adverse reactions to antibiotics, chemotherapy, and monoclonal antibodies. Her laboratory has studied how to reduce the immune response in patients who are sensitized to these classes of medications.

Dr. Laidlaw’s research focuses on treatments and desensitization options for patients with aspirin-exacerbated respiratory disease (AERD).

Dr. Wickner’s research centers on the role of electronic health records in communicating information about patient drug allergies.

Learn more about biomedical research at Brigham and Women’s Hospital:  


Maria C. Castells, MDMaria C. Castells, MD

Tanya M. Laidlaw, MDTanya M. Laidlaw, MD

Paige G. Wickner, MD,MPHPaige G. Wickner, MD,MPH

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